Well your post really started something. I'm quite intrigued by Krieger and these other "insulin skeptics" who have turned the spotlight away from insulin and onto ASP (acylation stimulating protein) as the primary hormone involved in fat accumulation. I'm intrigued, but still not convinced by their arguments. I've been engaged in an ongoing debate about this, not only on Krieger's Weightology site, but also on Jimmy Moore's low carb site, and on a new blog by one of the most vocal and articulate of the insulin skeptics, who goes by the pseudonym "CarbSane". For those interested in this debate, here are the links:"Does Insulin Deserve A Bad Reputation?" (Jimmy Moore)
- scroll half-way down the column to see my contribution"Insulin Wars" (My Carb Sane Asylum)
- a debate between me and Carbsane.
CarbSane and others argue that the role of insulin in fat storage has been overstated and misunderstood. CarbSane further contents that there is nothing special about lowcarb, but that weight loss is purely a matter of calories in minus calories out. And yet she herself eats a primarily low carb diet.
Thanks for this and please keep posting stuff like this!