I'm excited because I know I can finally can make a contribution to the group on this one. I take thyroid medication. I have been on it for a while, because I was tired all the time, had no energy, and was not loosing weight. When my doctor put me on it, I felt better within 2 weeks. Then, in a very subtle, slow way, I went back to my lethargic self 6 months later. My doctor insisted this time it was not my thyroid. I switched doctors, to an Endocrinologist who is a specialist in thyroid issues. He told me that thyroid hormone is a range, and I just needed to be higher in the range, as I was in the low to middle area. This meant that my dose went from 75 mcg (that's micrograms) of synthroid to 100 mcg I feel so very much better!! As you can tell, I am very born again about this. I can stay up past my children's 8:00 bedtime, and actually do things! I am also beginning to lose weight. So, my points are: if you are on thyroid medicine, you may need to go up slightly, and go to a great Endocrinologist.